Advantages And Disadvantages Of Stem Cells In Medicine – Human stem cell research is one of the most hotly debated topics in medicine and politics. Proponents and opponents have strong arguments to defend their position, and there is still a lot of uncertainty on this issue. Let’s look at some of the pros and cons of human stem cell research.
Most of us may have a general understanding of the stem cell research controversy, but we may not be aware of the specific issues that make it our most controversial issue. This is our time. There are many advantages and disadvantages, but before delving into them, it is important to explain what stem cell research is.
Advantages And Disadvantages Of Stem Cells In Medicine
Stem cell research refers to stem cells that have the ability to reproduce. Stem cells can develop into other types of cells such as kidney cells, liver cells, heart cells. Current clinical research focuses on two types of stem cells – mature and embryonic.
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Stem cells can develop into any type of cell in the human body known as totipotent. They have the power to build the whole body. Pluripotent stem cells have the ability to form all types of tissue found in the human body. These cells are found only at a certain stage (blastocyst) in human embryos.
Pluripotent cells have different regions, so they can give rise to a limited number of tissue types. Pluripotent stem cells are found in the fetus, in various adult tissues, and in the blood. Oligopotent stem cells have little capacity for regeneration and can only give rise to a limited number of other cells.
Of course, confusion will continue. Hopefully in the future there will be new scientific information that will have the benefit of not harming the right to human life. One must know that man must control technology, but surely there is no other way.
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Stem Cell Transplants
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Importance Of Stem Cells
Umbilical cord blood cells can be used to treat many diseases and conditions. They can restore the body’s natural defenses, which are often damaged by chemotherapy or radiation therapy. Umbilical cord blood (UCB) contains hematopoietic progenitor cells that give rise to various types of blood cells in the body, including red blood cells, lymphocytes, neutrophils, macrophages, and basophils.
Umbilical cord blood shows promise in treating a variety of diseases and conditions, including leukemia, lymphoma, anemia, and other medical problems.
Research shows that advertising can tip the balance and talk about what you think about it! Advantages of UCB: Advantages of umbilical cord blood stem cells (UCBSC) include their availability, safety information, and ease of collection by collecting the baby after cesarean delivery. Collection of UCBSCs does not require invasive procedures such as apheresis; So they do not cause any harm to mother and child. Another advantage is that low crops can be multiplied in culture to achieve higher yields for breeding.
Although they show great potential to treat various diseases and injuries, there are still limitations in their use that must be overcome before they can be used as therapy. This includes:
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What is best for back and joint pain? This is a controversial issue. The answer depends on who you ask. However, the devil is in the details [or facts]. I want to present the facts from which you can decide. I have compiled these facts in the table below and given a detailed explanation below.
Based on recent FDA guidelines, bone marrow stem cells are the most acceptable of the commercially available stem cells. These cells fall under the “same surgery” exemption.
If a doctor removes stem cells from a patient’s body and disposes of them on the same day, the procedure is called “same surgery.” Bone marrow stem cells qualify for this exemption, but bone marrow stem cells do not.
If stem cells are eligible for “equivalent surgical treatment,” the only guidelines we need to follow to satisfy the FDA are four “minimum therapeutic” procedures. This means that the city should not be overstimulated. When the bone marrow cells are removed from the iliac crest [hip bone], we keep them [to increase the number of stem cells per milliliter]. Centrifugation is considered “minimal handling” by the FDA.
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Because umbilical cord stem cells do not meet the “same surgical method” exception, they must follow several guidelines to be FDA compliant. These conditions….
Dr. Philippe Hernico, a French surgeon, has been performing stem cell treatments using bone marrow stem cells for over 30 years. He has published several studies showing that bone marrow stem cells help many patients with pain. In one of his unique studies, he showed that bone marrow stem cells resulted in better patient satisfaction compared to total knee replacement. In addition, knee replacement patients had many complications. He also showed recovery based on x-ray images as shown below. These pictures are from his study.
Dr. Pettin did another important study on bone marrow cells and back pain. By injecting bone cells into lumbar discs, 81% of patients experienced pain relief and 76% of patients avoided fusion. It has also been shown that these cells can regenerate into discs as shown below. Here are the MRI images from his exam. Yellow lines show discs, and the disc in [B] image is brighter to indicate regeneration.
This is a compilation of all studies that used bone marrow cells to treat knee arthritis.
Autologous Vs. Allogeneic Cell Therapy
Early evidence shows that stem cell therapy may be effective. It also works in the long term. Dr. Hernikow’s research on knees showed that after 12 years, patients who received bone cells had no pain. Likewise, Dr. Pett’s study showed that patients with back pain were pain-free even after 5 years. How many clinical studies have been published on the effectiveness of umbilical cord cells to treat pain?
As I mentioned earlier, Dr. Hernico has been performing bone marrow stem cell procedures for over 30 years. He recently posted his experience and said he had no problems. Another major study by Dr.Centeno also stated that marrow stem cells are very safe.
On the other hand, we know that umbilical cord stem cells are not safe. CNN and the NY Times recently reported 12 serious illnesses after umbilical cord stem cells were used to treat pain. The infections were so severe that these patients were hospitalized, some for up to 2 months. The FDA has recalled specific products that have caused these illnesses. Because these diseases are caused by abuse and poor donor screening, the CDC [Centers for Disease Control and Prevention] requires these patients to be tested for hepatitis C, hepatitis B, and HIV.
Since the umbilical cord cells come from other people, the risk of infection is low. HLA-A imbalance can cause minor complications to major events such as death due to GVHD [infection and disease].
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Umbilical cord stem cells products do not contain stem cells. They have something to grow. It should be called growth factor therapy, not stem cell therapy.
Umbilical cord blood contains few mesenchymal stem cells. These cells are needed to process pain. They contain many hemopoietic cells
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